Topical treatment with a cathepsin G inhibitor, β‐keto‐phosphonic acid, blocks ultraviolet irradiation‐induced basement membrane damage in hairless mouse skin

ConclusionOur present study showed the possible involvement of CTSG in UV ‐induced basement membrane damage in skin through topical treatment with a cathepsin G inhibitor, KPA. Thus, inhibition of CTSG may be a useful strategy for the prevention of UV‐induced basement membrane damage and photoaging.This article is protected by copyright. All rights reserved.

Source: Photodermatology, Photoimmunology and Photomedicine - November 10, 2018 Category: Radiology Authors: Novi Kusumaningrum, Jang ‐Hee Oh, Dong Hun Lee, Chang‐Yup Shin, Jee‐Hee Jang, Yeon Kyung Kim, Jin Ho Chung Tags: Original Article Source Type: research