Streptozotocin-induced vascular and biochemical changes in rats: Effects of rosiglitazone vs. metformin

In conclusion both drugs show beneficial effects against the vascular dysfunction associated with hyperglycaemia which might be related to their euglycaemic activity in addition to anti-oxidant property of rosiglitazone and a direct effect of metformin on vascular smooth muscle.
Source: Bulletin of Faculty of Pharmacy, Cairo University - Category: Drugs & Pharmacology Source Type: research