Screening and Identification of Pregnancy Zone Protein (PZP) and Leucine ‐Rich Alpha‐2‐Glycoprotein (LRG) as Potential Serum Biomarkers for Early‐onset Myocardial Infarction using Protein Profile Analysis

Conclusions and clinical relevance: We identified five differential serum proteins in early ‐onset MI using proteomic analysis. Lipoprotein‐related biomarkers further demonstrate the close relationship between lipid metabolism and the disease. Inflammation‐associated LRG and PZP may be novel biomarkers of the disease. In addition, changes in these proteins may partly reveal the possi ble mechanisms in the pathogenesis and pathophysiology of early‐onset MI.This article is protected by copyright. All rights reserved

Source: Proteomics. Clinical Applications - November 8, 2018 Category: Biochemistry Authors: Chao Xuan, Hui Li, Le ‐Le Li, Qing‐Wu Tian, Qing Wang, Bei‐Bei Zhang, Jun‐Jie Guo, Guo‐Wei He, Li‐Min Lun Tags: Research Article Source Type: research