Effects of multiple exposures to sevoflurane at sub-MAC doses on neuroapoptosis and cognitive function during the neonatal period

Conclusions Sevoflurane exposure of neonatal rats for short and repeated time intervals induces neuronal death probably due to apoptosis, through caspase-3 activation. This results in learning deficit, particularly in terms of spatial memory acquisition.
Source: Colombian Journal of Anesthesiology - Category: Anesthesiology Source Type: research