Hepatic transcriptome of the euryhaline teleost Japanese seabass (Lateolabrax japonicus) fed diets characterized by α-linolenic acid or linoleic acid

In conclusion, under the present experimental conditions, a high level of dietary α-linolenic acid tended to suppress lipid transport and protein biosynthetic processes in the liver of Japanese seabass at the gene expression level.Graphical abstractTo investigate the different effects of dietary α-linolenic acid (ALA) and linoleic acid (LA) on the euryhaline fish species Japanese seabass, a feeding trial followed by hepatic transcriptome assay was conducted. Compared to LA, ALA up-regulated transcription of 49 unigenes and down-regulated those of 311 unigenes, which were primarily enriched in pathways related to lipid transport, protein synthesis, and complement and coagulation cascades.
Source: Comparative Biochemistry and Physiology Part D: Genomics and Proteomics - Category: Genetics & Stem Cells Source Type: research