Giant cell tumour of the bone treated with denosumab: How has the blood supply and oncological prognosis of the tumour changed?

ConclusionDenosumab treatment can reduce the blood supply of giant cell tumour. The sacral or pelvic lesions changed more significantly than limb lesions. The surgical plan downstaging can also be achieved. The clear margin after denosumab treatment facilitated tumour resection but, increased difficult in curettage surgery, and high recurrence rate of sacral tumour is being concerned.
Source: Journal of Orthopaedic Translation - Category: Orthopaedics Source Type: research