Amniotic fluid proteomic signatures of cervical insufficiency and their association with length of latency

ConclusionIn this pilot study, significant differences in the amniotic fluid proteomic profiles in cases of cervical insufficiency compared to genetic amniocentesis were observed. Proteomic signatures were predictive of achieving latency> 1  week after diagnosis of cervical insufficiency. These preliminary findings suggest that proteomic analysis may be of value in predicting outcome following cervical insufficiency and warrants further validation in larger studies.

Source: American Journal of Reproductive Immunology - October 25, 2018 Category: Allergy & Immunology Authors: Rachelle N. M. Govia, Kenzie D. Birse, Shadi Sepehri, Ehsan Khafipour, Savas M. Menticoglou, Adam D. Burgener, Vanessa Poliquin Tags: ORIGINAL ARTICLE Source Type: research