Risk of neurosyphilis in HIV ‐infected persons with syphilis lacking signs or symptoms of central nervous system infection

ConclusionsThis large number of potentially unnecessary LPs, along with heterogeneity of presentation, and the never ‐nil risk of asymptomatic neurosyphilis should be incorporated into clinical decision‐making. The majority of PLWH presenting with a serological diagnosis of syphilis, but no neurological signs or symptoms, do not necessarily require an LP for an evaluation of asymptomatic neurosyphilis.

Source: HIV Medicine - November 7, 2018 Category: Infectious Diseases Authors: L Rotman, X Luo, A Thompson, ME Mackesy ‐Amiti, LR Young, JD Young Tags: Original Research Source Type: research