Liver Transplant Listing in Pediatric Acute Liver Failure: Practices and Participant Characteristics

Conclusion: The cumulative incidence of listing for and receiving LT decreased throughout the PALF study without an increase in the cumulative incidence of death. While all participants fulfilled entry criteria for PALF, significant differences were noted between participants listed for LT and those deemed “not sick enough” as well as those who were “medically unsuitable.” Having an indeterminate diagnosis and a requirement for cardiopulmonary support appeared to influence decisions toward listing; optimizing listing decisions in PALF may reduce the frequency of LT without increasing the frequ ency of death.

Source: Hepatology - November 1, 2018 Category: Internal Medicine Authors: James E. Squires, David A. Rudnick, Regina M. Hardison, Simon Horslen, Vicky L. Ng, Estella M. Alonso, Steven H. Belle, Robert H. Squires; for the Pediatric Acute Liver Failure Study Group Tags: Original Article Source Type: research