Impact of maternal body mass index and fetal sex on Th1:Th2 cell ratio in preeclampsia

Objectives: Preeclampsia (PE) has an imbalance in the T helper 1 (Th1)/T helper 2 (Th2) cytokine balance with a deviation toward the Th1 cytokine profile rather than a shift toward Th2 in normal pregnancy, even though the reason has not yet been clarified. The relationship between fetal sex and PE has been debated. Our hypothesis that maternal and/or fetal and/or placental factors might cause or contribute to the occurrence of PE.
Source: Journal of Reproductive Immunology - Category: Allergy & Immunology Authors: Source Type: research