Flow cytometric analysis of NK22 cells function in peripheral blood and endometrium obtained from women with recurrent pregnancy loss

Problem: It is considered that NK22 cells might mediate mucosal immune defense in several organ. In response to pathogen, IL-23 stimulates NK22 cells to secrete IL-22. It is only reported that NK22 cells were present in the uterine mucosa. To examine the NK22 function, we investigated the production and relation of IL-22 and the other cytokines using endometrium (EM) and peripheral blood (PB) NK cells of women with recurrent pregnancy loss (RPL).
Source: Journal of Reproductive Immunology - Category: Allergy & Immunology Authors: Source Type: research