Goshajinkigan completely recover the severe aspermatogenesis after busulfan treatment in mice

Busulfan (Myleran, 1,4-butanediol methanesulfonate) is used as anticancer chemotherapeutic drugs in childhood and adult chronic myelogenous leukemia as well as an immunosuppressive agent before bone marrow transplantation. It is well known that the male infertility including spermatogenesis disturbance is one of side effect. There is little information about therapeutic drugs on male infertility after busulfan treatment. Some traditional Chinese medicines have been administered for improving spermatogenesis and have been extensively used to treat male infertility.
Source: Journal of Reproductive Immunology - Category: Allergy & Immunology Authors: Source Type: research