Urokinase-type plasminogen activator (uPA) system and invasion of early human extravillous trophoblast is regulated by hypoxia induced factor (HIF) pathway

In this study, we investigated the connection of hypoxia-induced factor (HIF) and uPA on primary EVTs to define the intracellular and extracellular protease pathway on early pregnancy.

Source: Journal of Reproductive Immunology - November 1, 2014 Category: Allergy & Immunology Authors: N. Koike, T. Tsunemi, J. Akasaka, A. Shigemitsu, C. Yoshimoto, K. Naruse, H. Kobayashi Source Type: research