Neonatal alloimmune thrombocytopenia caused by maternal past lymphocytes immunotherapy: a case report
Background: Neonatal alloimmune thrombocytopenia (NAIT) occurs as a result of maternal alloimmunization against paternally inherited antigens on fetal platelets. Platelets express platelet specific antigens (HPA) along with human leucocyte antigens (HLA) class I. Especially anti-HLA class I antibodies are often produced by pregnancy and blood transfusion. Here we report a rare case of neonatal thrombocytopenia observed in a female infant delivered by woman with history of lymphocytes immunotherapy for habitual abortion.
Source: Journal of Reproductive Immunology - Category: Allergy & Immunology Authors: M. Ito, S. Soeda, S. Yoneda, Y. Ono, N. Yoneda, A. Shiozaki, S. Saito Source Type: research
More News: Allergy & Immunology | Blood Transusion | Perinatology & Neonatology | Pregnancy | Thrombocytopenia