Genotyping analysis for the 46C/T polymorphism of coagulation factor XII and the involvement of factor XII activity in patients with recurrent pregnancy loss

Objective: We previously found that low FXII activity, but not an associated common genetic polymorphism, 46C/T, was linked to PRL. There is no reported study indicating the influence of the FXII SNP on further pregnancy outcome. Thus, we conducted this cross-sectional and cohort study.

Source: Journal of Reproductive Immunology - November 1, 2014 Category: Allergy & Immunology Authors: E. Hashimoto, T. Ebara, C. Yamada-Namikawa, T. Kitaori, N. Suzumori, K. Katano, Y. Ozaki, M. Sugiura-Ogasawara Source Type: research