Transcranial direct current stimulation (tDCS) modulates biometric and inflammatory parameters and anxiety-like behavior in obese rats

Obesity is a multifactorial disease associated with metabolic dysfunction and the prevention and treatment of obesity are often unsatisfactory. Transcranial direct-current stimulation (tDCS) is a non-invasive brain stimulation technique that has proven promising in the treatment of eating disorders such as obesity. We investigate the effects of tDCS on locomotor and exploratory activities, anxiety-like and feeding behavior, and levels of brain-derived neurotrophic factor (BDNF), IL (interleukin)-10, IL-1 β, and tumor necrosis factor-alpha (TNF-α) in the cerebral cortex of obese rats.

Source: Neuropeptides - October 30, 2018 Category: Neuroscience Authors: Carla de Oliveira, Joice Soares de Freitas, Isabel Cristina de Macedo, Vanessa Leal Scarabelot, Roberta Str öher, Daniela Silva dos Santos, Andressa de Souza, Felipe Fregni, Wolnei Caumo, Iraci L.S. Torres Source Type: research