The influence of interleukin‐7 receptor α‐chain haplotypes on outcome after allogeneic hematopoietic cell transplantation

Summary
We investigated the influence of IL‐7 receptor α‐chain (IL‐7Rα) gene haplotypes in donors on the outcome of haematopoietic cell transplantation (HCT). Unlike the association between single donor SNPs and HCT outcome found previously, only trends towards association were found here, due to ‘dilution’ of SNPs into haplotypes.

Source: International Journal of Immunogenetics - October 1, 2014 Category: Genetics & Stem Cells Authors: B. Broux, Z. Shamim, T. Wang, S. Spellman, M. Haagenson, P. Stinissen, L. P. Ryder, K. Müller, N. Hellings Tags: Short Communication Source Type: research