Changes of Bax, Bcl-2, chemokine receptor-2, monocyte chemoattractant protein-1, and transforming growth factor β1 genes in the left ventricle of spontaneously hypertensive rat after losartan treatment.

Conclusion: After losartan treatment Bax, CCR-2, MCP-1,TGF-β1, PERK, connexin 43 protein and kallikrein mRNA gene expressions were reduced in SHR. Losartan decreased inflammation and apoptosis. PMID: 30360036 [PubMed - as supplied by publisher]
Source: Korean Journal of Pediatrics - Category: Pediatrics Tags: Korean J Pediatr Source Type: research