Outcomes of Fosfomycin Use in Ceftriaxone-Resistant Enterobacteriaceae Urinary Tract Infection in the Elderly
Fosfomycin is a cell-wall active antibiotic with bactericidal activity against many gram-positive and negative bacteria. One dose of 3g oral Fosfomycin is indicated for uncomplicated cystitis in females [1]. Increasingly, it is used to treat cystitis caused by drug-resistant organisms but data on patients with renal impairment are lacking. We conducted a retrospective study to determine the safety and efficacy of fosfomycin in treating cystitis caused by extended spectrum beta-lactamase (ESBL) Enterobacteriaceae in a 1400-bed teaching hospital.
Source: International Journal of Antimicrobial Agents - Category: Drugs & Pharmacology Authors: Wei Ming Quek, Christine B. Teng, Yan Zhi Tan, Kelly Chong, David C. lye, Tat Ming Ng Source Type: research
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