Additional B-cell deficiency does not affect growth and angiogenesis of ectopic human endometrium in T-cell-deficient endometriosis mouse models during long-term culture

Endometriosis is a gynecological disease characterized by the presence of endometrial tissue outside the uterine cavity. It comprises peritoneal, ovarian, and deep-infiltrating endometriosis leading to pelvic pain, dysmenorrhea, and subfertility (Nnoaham et al., 2011). This estrogen-dependent disease affects 10–15% of women of reproductive age (Hey-Cunningham et al., 2013), and its prevalence is described in up to 50% of women undergoing assisted reproduction (Eskenazi and Warner, 1997).
Source: Journal of Reproductive Immunology - Category: Allergy & Immunology Authors: Source Type: research