Characterization of proopiomelanocortin in the snakeskin gourami () and its expression in relation to food intake

Proopiomelanocortin (POMC) is the precursor of several hormones involved in physiological systems including feed intake. The snakeskin gourami (Trichopodus pectoralis) POMC complementary DNA (TpPOMC) was cloned and characterized. Phylogenetic analysis showed that TpPOMC was clustered in a major POMC lineage in fish. Analysis of the Ka to Ks ratios for the entire POMC sequence and for each hormonal segment suggested that different POMC-derived peptide segments were subject to different evolutionary pressures.

Source: Domestic Animal Endocrinology - June 30, 2014 Category: Endocrinology Authors: S. Boonanuntanasarn, A. Jangprai, G. Yoshizaki Source Type: research