Expression of variant transcripts of the potassium channel tetramerization domain-containing 15 gene and their association with fatness traits in chickens

The aim of this study was to characterize the structure, expression, and biological functions of potassium channel tetramerization domain containing 15 (KCTD15) in chickens. We compared the KCTD15 expression level in samples of hypothalamic, adipose, and liver tissue of Xinghua chickens that were maintained on different dietary status. An association analysis of KCTD15 gene variant transcripts with fatness traits in a F2 resource population of chickens was performed. Three KCTD15 transcripts were identified in which the complete transcript was predominantly expressed in adipose tissue and the hypothalamus.

Source: Domestic Animal Endocrinology - September 30, 2014 Category: Endocrinology Authors: S.S. Liang, H.J. Ouyang, J. Liu, B. Chen, Q.H. Nie, X.Q. Zhang Source Type: research