Differential gene expression and immunolocalization of platelet-derived growth factors and their receptors in caprine ovaries

This study evaluated the mRNA expression and immunolocalization of all members of the platelet-derived growth factor (PDGF) family in caprine ovaries by qPCR and immunohistochemistry, respectively. Detectable levels of PDGF-A mRNA were not observed in primordial follicles. Higher levels of PDGF-B mRNA were observed in primary follicles than in primordial follicles (P < 0.05). PDGF-D mRNA levels were higher in secondary follicles than in the other preantral follicle categories (P < 0.05). PDGF-B mRNA expression was higher than PDGF-C mRNA expression in primary follicles (P < 0.05).

Source: Domestic Animal Endocrinology - October 20, 2014 Category: Endocrinology Authors: I.R. Brito, A.D. Sales, G.Q. Rodrigues, C.H. Lobo, S.V. Castro, A.W.B. Silva, A.A.A. Moura, J.R.V. Silva, A.P.R. Rodrigues, J.R. Figueiredo Source Type: research