Resistance mechanism of the oncogenic β3‐αC deletion mutation in BRAF kinase to dabrafenib and vemurafenib revealed by molecular dynamics simulations and binding free energy calculations

Chemical Biology&Drug Design, EarlyView.

Source: Chemical Biology and Drug Design - October 9, 2018 Category: Biology Authors: Yuzhen Niu, Yan Zhang, Xiaojun Yao Source Type: research