Cutibacterium acnes protects Candida albicans from the effect of micafungin in biofilms

Candida albicans is an opportunistic pathogenic yeast as well as a commensal organism of the oral cavity, gastrointestinal and genitourinary tracts, and skin [1]. Immunocompromised patients can develop superficial candidiasis (oropharyngeal, vaginal, etc.) and candidaemia [2]. In the USA, Candida spp. is the fourth leading cause of nosocomial bloodstream infections, and 50.7% of these infections are attributed to C. albicans [3]. In fact, many of these nosocomial bloodstream infections may involve more than one species of Candida and/or bacteria, and one-half of them may be linked to implanted medical devices (IMDs) [4,5].
Source: International Journal of Antimicrobial Agents - Category: Drugs & Pharmacology Authors: Tags: Themed Issue: Recent Advances in Antimicrobial and Bacterial Resistance Source Type: research