What Is the Best Electrophysiologic Marker of the Outcome of Subthalamic Nucleus Stimulation in Parkinson Disease?

Deep brain stimulation of the subthalamic nucleus (STN) is advocated in patients with advanced Parkinson disease. Intraoperative microelectrode recordings (MER) and stimulation or imaging are applied to confirm electrode targeting. The study objective was to evaluate which intraoperative electrophysiologic marker, MER, stimulation, or local field potentials (LFP) was the most predictive of the clinical efficacy.

Source: World Neurosurgery - September 18, 2018 Category: Neurosurgery Authors: Colette Bo ëx, Rémi Tyrand, Judit Horvath, Vanessa Fleury, Sarvenaz Sadri, Marco Corniola, Pierre R. Burkhard, Shahan Momjian Tags: Original Article Source Type: research