Detection of ischemic changes in the vascular endothelial cell layer by using microelectrochemical impedance spectroscopy

Endothelial cells, constituting the endothelial layer, are located in the inner monolayer of the circulatory system, lymphatic system, and gastrointestinal system. The endothelial cells have important roles within each system. In particular, endothelial cells have important roles in the vascular system, including maintaining the vasomotor tone and hemostasis. In this context, dysfunction of endothelial cells is one of the critical factors in cardiovascular disease [1]. The endothelial cell dysfunction, which is caused by endothelial cell injury, leads to problems with hemostasis and the nitric oxide production mechanism.

Source: Medical Engineering and Physics - October 11, 2018 Category: Biomedical Engineering Authors: Jung-Joon Cha, Jinhwan Kim, Joho Yun, Yangkyu Park, Jong-Hyun Lee Tags: Short Communication Source Type: research