Deep Brain Stimulation of the Hypothalamus Leads to Increased Metabolic Rate in Refractory Obesity

Obesity has become a worldwide epidemic, with very few long-term successful treatment options for refractory disease. Deep brain stimulation (DBS) of the bilateral lateral hypothalamus (LH) in refractory obesity has been performed safely, but questions remain regarding optimal settings and its effects on metabolic rate. The goals of this experiment were to determine optimal DBS settings and then to determine the actual effect of optimal stimulation on energy expenditure.

Source: World Neurosurgery - October 10, 2018 Category: Neurosurgery Authors: Alexander C. Whiting, Elizabeth F. Sutton, Corey T. Walker, Jakub Godzik, Joshua S. Catapano, Michael Y. Oh, Nestor D. Tomycz, Eric Ravussin, Donald M. Whiting Tags: Original article Source Type: research