Differences in Pituitary-Adrenal Reactivity in Black and White Men with and without Alcohol Use Disorder

Individuals with alcohol use disorder (AUD) display a wide array of neurophysiological disturbances, including dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis. However, other contributing factors have been shown to influence this dysregulation including sex (Adinoff et al., 2010; Kudielka& Kirschbaum, 2005) and psychopathology (Brady et al., 2006). Racial minority status, although implicated in altered HPA axis function (Chong et al., 2008; Skinner et al., 2011), has never been evaluated as a potential factor in AUD-related HPA axis dysregulation.

Source: Psychoneuroendocrinology - October 9, 2018 Category: Psychiatry Authors: Julianne L. Price, Ian R. Frazier, Ben Lewis, Robrina Walker, Martin A. Javors, Sara Jo Nixon, Bryon Adinoff Source Type: research