Extended Blood Group Molecular Typing and Next-Generation Sequencing

Several high-throughput multiplex blood group molecular typing platforms have been developed to predict blood group antigen phenotypes. These molecular systems support extended donor/patient matching by detecting commonly encountered blood group polymorphisms as well as rare alleles that determine the expression of blood group antigens. Extended molecular typing of a large number of blood donors by high-throughput platforms can increase the likelihood of identifying donor red blood cells that match those of recipients.

Source: Transfusion Medicine Reviews - August 28, 2014 Category: Hematology Authors: Zhugong Liu, Meihong Liu, Teresita Mercado, Orieji Illoh, Richard Davey Source Type: research