A Mechanistic Approach to the Diagnosis and Management of Atypical Hemolytic Uremic Syndrome
Until recently, atypical hemolytic uremic syndrome (aHUS), conventionally defined in the pediatric literature as a syndrome of the triad of renal failure, microangiopathic hemolytic anemia, and thrombocytopenia without a prodrome of hemorrhagic diarrhea, has received little attention in adult practice because the patients are commonly given the diagnosis of thrombotic thrombocytopenic purpura (TTP) or TTP/HUS and treated as TTP with plasma exchange, augmented in refractory cases with rituximab and sometimes even splenectomy.
Source: Transfusion Medicine Reviews - Category: Hematology Authors: Han-Mou Tsai Source Type: research
More News: Anemia | Hematology | Hemolytic Uremic Syndrome (HUS) | Microangiopathic Hemolytic Anemia | Pediatrics | Renal Failure | Rituxan | Splenectomy | Thrombocytopenia