De novo thrombotic microangiopathy after non-renal solid organ transplantation
This article presents the first literature review on TMA following non-renal solid organ transplantation (SOT). Ischemia–reperfusion, immunosuppressive drugs, acute interfering disease and a relative deficiency of the von Willebrand factor (vWF) cleaving protease (ADAMTS13) appear to play a major role in its pathogenesis. De novo TMA occurs in 4.0% of liver and 2.3% of lung transplant recipients, whereas the incidence remains unknown after intestinal transplantation.
Source: Blood Reviews - Category: Hematology Authors: Annelies Verbiest, Jacques Pirenne, Daan Dierickx Tags: REVIEW Source Type: research
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