Oligopeptidases activity in bipolar disorder: ndel1 and angiotensin i converting enzyme

Abnormal activity of two enzymes relevant to neurodevelopment, namely nuclear-distribution element-like 1 (Ndel1) and angiotensin I-converting enzyme (ACE), was reported in individuals with schizophrenia; to our knowledge, these oligopeptidases were never measured in bipolar disorder (BD). Aims: Evaluate the enzyme activity of Ndel1 and ACE in euthymic individuals with BD type 1 which was compare to healthy control (HC) group.

Source: Journal of Affective Disorders - October 6, 2018 Category: Neurology Authors: Caroline Dal Mas, Michelle S. Carvalho, Lucas A. Marins, Camila M. Yonamine, Quirino Cordeiro, Roger S. McIntyre, Rodrigo B. Mansur, Elisa Brietzke, Mirian A.F. Hayashi Source Type: research