Chronic Stress Exposure, Diurnal Cortisol Slope, and Implications for Mood and Fatigue: Moderation by Multilocus HPA-Axis Genetic Variation

Some are more likely than others to succumb to health problems following stress exposure. Genetic risk likely contributes to this variability, but much is unknown about specific physiological mechanisms bridging genetic variation to health-related phenotypes. Here, we explore an important potential factor, diurnal cortisol slope, in relation to chronic stress and multilocus HPA-axis genetic variation.

Source: Psychoneuroendocrinology - October 6, 2018 Category: Psychiatry Authors: Lisa R. Starr, Kimberly Dienes, Y. Irina Li, Zoey A. Shaw Source Type: research