Prevalence of HLA‐DQA1 alleles and haplotypes in blood donors resident in Wales

Summary
Two hundred and fifty‐four normal blood donors, from a largely UK European population, were sequence‐based typed for HLA‐A, HLA‐B, HLA‐C, HLA‐DRB1, HLA‐DQA1 and HLA‐DQB1. The fit to Hardy–Weinberg expectations was good for all loci (all P values >0.5). Fifteen DQA1 alleles were identified to the second field. DQA1 carriage, allele and DQA1–DQB1 and DRB1–DQA1–DQB1 haplotype frequencies, linkage disequilibria and related values are presented.

Source: International Journal of Immunogenetics - October 1, 2014 Category: Genetics & Stem Cells Authors: A. J. Lemin, C. Darke Tags: Short Communication Source Type: research