Pharmacokinetic analysis of the chronic administration of the inert gases Xe and Ar using a physiological based model

ConclusionsThe use of standard pharmacokinetics parameters such as area under the curve would be more appropriate to assess the delivered dose of chronic gas administration than the gas concentration in the delivery system that is typically reported in the scientific literature because species and gas differences can result in very different delivered doses.
Source: Medical Gas Research - Category: Biomedical Science Source Type: research