Update on the epidemiology and disease outcome of Familial Mediterranean fever

Publication date: Available online 29 September 2018Source: Best Practice & Research Clinical RheumatologyAuthor(s): Seza ÖzenAbstractAutoinflammatory diseases (AIDs) are diseases of the innate immune system, with clinical and laboratory evidence of attacks of inflammation. The more common AIDs are those associated with periodic fevers: Familial Mediterranean fever (FMF); Mevalonate Kinase Deficiency (MKD)/Hyperimmunoglobulin D Syndrome (HIDS); Cryopyrin-associated Autoinflammatory Syndrome (CAPS); and Tumor Necrosis Factor Receptor-Associated Periodic Syndrome (TRAPS). Classification criteria have been developed for all these types. FMF is the most common AID worldwide with a particularly high prevalence in the Eastern Mediterranean region. Environmental factors are thought to affect the course of the disease. Outcome measures are being developed for AIDs.
Source: Best Practice and Research Clinical Rheumatology - Category: Rheumatology Source Type: research