Automatic Grading of Prostate Cancer in Digitized Histopathology Images: Learning from Multiple Experts

With an estimated number of 161,360 new cases and 26,730 deaths in 2017, prostate cancer (PCa) is the second most commonly diagnosed cancer, and third most common cause of cancer death among American men Siegel et  al. (2017). PCa is a heterogeneous disease and is manifested in a diverse range of histologic patterns. The Gleason score Gleason (1966) is currently the most common grading system of prostate adenocarcinoma, and proven to be a clinically relevant prognostic marker. The grade is determined by path ologists based on the glandular architectural features observed in haematoxylin and eosin (H&E) stained samples.

Source: Medical Image Analysis - September 24, 2018 Category: Radiology Authors: Guy Nir, Soheil Hor, Davood Karimi, Ladan Fazli, Brian F. Skinnider, Peyman Tavassoli, Dmitry Turbin, Carlos F. Villamil, Gang Wang, R. Storey Wilson, Kenneth A. Iczkowski, M. Scott Lucia, Peter C. Black, Purang Abolmaesumi, S. Larry Goldenberg, Septimiu Source Type: research