Lymphocytic gastritis in a child with hemophagocytic syndrome

We describe a case of LG in a 2-year-old child who died of a hepatitis A virus-induced hemophagocytic syndrome (HPS). LG was diagnosed retrospectively at the postmortem examinat ion. The stomach showed diffuse thickening of mucosal folds with small erosions. On microscopic examination prominent intraepithelial infiltration of the gastric mucosa by T-cells was found, but the small bowel showed no villous atrophy, excluding the diagnosis of celiac disease. To the best of our knowledge, this is the first description of a case of LG associated with an infection-related HPS.
Source: Annals of Diagnostic Paediatric Pathology - Category: Pathology Source Type: research