Effects of sucralose on insulin and glucagon-like peptide-1 secretion in healthy subjects: a randomized, double-blind, placebo-controlled trial

As a result of the rapid increases in the prevalence of type 2 diabetes mellitus and obesity, non-nutritive sweeteners (NNS) have become popular as alternatives to added sugars because they contain no or fewer calories while preserving palatability [1,2]. Unexpectedly, an accumulation of studies have suggested that NNS may increase the risk of excessive weight gain [3], metabolic syndrome [4,5], and type 2 diabetes mellitus [6,7]. There are several potential mechanisms that may induce NNS to cause glucose intolerance.

Source: Nutrition - April 20, 2018 Category: Nutrition Authors: Amornpan Lertrit, Sasinee Srimachai, Sunee Saetung, Suwannee Chanprasertyothin, La-or Chailurkit, Chatvara Areevut, Pornalat Katekao, Boonsong Ongphiphadhanakul, Chutintorn Sriphrapradang Tags: Applied nutritional investigation Source Type: research