Diet and physical activity in the association between depression and metabolic syndrome: Constances study
Depression is associated with an increased risk of metabolic syndrome that contributes to the poor cardiovascular health of depressed individuals. A meta-analysis showed that individuals with depression had a 1.5 times higher odds of having a metabolic syndrome (Vancampfort et al., 2014). Although the exact mechanisms underlying this association are poorly known, several hypotheses have been proposed. Depression and metabolic syndrome may share some common alterations of the stress system which could lead to a low grade inflammatory state and to oxidative stress which damages the neurons as well as the pancreatic cells and the endothelium (Marazziti et al., 2014).
Source: Journal of Affective Disorders - Category: Neurology Authors: Joane Matta, Nicolas Hoertel, Emmanuelle Kesse-Guyot, Marie Plesz, Emmanuel Wiernik, Claire Carette, S ébastien Czernichow, Frédéric Limosin, Marcel Goldberg, Marie Zins, Cédric Lemogne Tags: Research paper Source Type: research
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