Successful management with fosfomycin  + ceftazidime of an infection caused by multiple highly-related subtypes of multidrug-resistant and extensively drug-resistant KPC-producing Serratia marcescens

Multidrug-resistant (MDR) and extensively drug-resistant (XDR) Serratia marcescens infections are increasing in several hospital wards around the world [1 –3], probably due to the recent use of colistin to combat Gram-negative carbapenem-resistant isolates [1,3,4]. Here we describe a particular case of S. marcescens infection from a single patient (P1) during 4 months of hospitalisation. Nine S. marcescens strains (SmP1–SmP9) isolated from consecu tive bone and soft tissue samples of P1 were subjected to antibiotyping and molecular studies (Table 1).

Source: International Journal of Antimicrobial Agents - August 6, 2018 Category: Drugs & Pharmacology Authors: Cecilia Rodr íguez, Silvina Brengi, Mariel Agustina Cáceres, Silvana Mochi, María Rosa Viñas, Constanza Antich Rizza, Graciela Merletti, Elena Bru, José Daniel Assa, Raúl Ricardo Raya, Daniela Centrón Tags: Letter to the Editor Source Type: research