The effects of pressure intervention on wound healing and scar formation in a Bama minipig model

Hypertrophic scars (HSs) are pathological tissue structures resulting from aberrations in physiological wound healing after injury to the deep dermis resulting from burns, severe trauma or surgical procedures [1,2]. Excessive scarring is usually characterized by over-proliferation of fibroblasts, abnormal synthesis and degradation of extracellular matrix (ECM), disorders in regulatory cytokines and abnormal neovascularization [3 –6]. Hypertrophic scars are generally raised, red, hard whilst in the form of a contracture, cause itching and painful.

Source: Burns : Journal of the International Society for Burn Injuries - September 28, 2018 Category: Cosmetic Surgery Authors: Baimei Liu, Yang Liu, Li Wang, Chunsheng Hou, Meiwen An Source Type: research