Pharmacokinetics of 400 mg Locally Infiltrated Ropivacaine After Total Knee Arthroplasty Without Perioperative Tourniquet Use
Conclusions
Although great interindividual variability in ropivacaine concentration was found, both total and unbound maximum serum concentrations remained below the assumed systemic toxic thresholds in all samples.
Clinical Trial Registration
This study was registered at Netherlands Trial Registry (http://www.trialregister.nl), trial ID NTR6306.
Source: Regional Anesthesia and Pain Medicine - Category: Anesthesiology Tags: Regional Anesthesia and Acute Pain: Original Articles Source Type: research
More News: Anesthesia | Anesthesiology | Clinical Trials | Netherlands Health | Pain | Study | Toxicology