A Study for the Mechanism of Sensory Disorder in Restless legs Syndrome based on Magnetoencephalography

In spite of the relatively high incidence rate, the etiology and pathogenesis of restless legs syndrome (RLS) are still unclear. Long-term drug treatments fail to achieve satisfying curative effects, which is reflected by rebound and augmentation of related symptoms. An electrophysiological endophenotype experiment was done to investigate the mechanism of somatosensory disorder among RLS patients. Together with 15 normal subjects as the control group, with comparable ages and genders to the RLS patients, 15 primitive RLS patients were scanned by Magnetoencephalography (MEG) under natural conditions, and the somatosensory evoked magnetic field (SEF) with single and paired stimuli, was also measured.

Source: Sleep Medicine - September 21, 2018 Category: Sleep Medicine Authors: Haoxiang Yang, Li Wang, Xin Li, Kun Wang, Yue Hou, Xiating Zhang, Zheng Chen, Chunyan Liu, Chunli Yin, Siqi Wu, Qian Huang, Yicong Lin, Yan Bao, Yuanyuan Chen, Yuping Wang Tags: Original Article Source Type: research