Malignant testicular germ cell tumors in children and adolescents: The AIEOP (Associazione Italiana Ematologia Oncologia Pediatrica) protocol

Testicular germ cell tumors (TGCT) are rare in children, and histologically and genetically similar to extragonadal tumors [1], whereas in adolescents they reveal genetic and clinical patterns similar to the disease in adults. These differences have led to TGCT being classified as type I for children with yolk sac tumor (YST) and/or teratoma (T) or type II for adolescents and young men with other, pure or mixed, sub entities [2]. In a previous Italian study [3], 36 TGCT patients ( ≤16 years old) underwent surgery, with or without radiotherapy and carboplatin-based chemotherapy (CT).
Source: Urologic Oncology: Seminars and Original Investigations - Category: Urology & Nephrology Authors: Tags: Original article Source Type: research