Malignant testicular germ cell tumors in children and adolescents: The AIEOP (Associazione Italiana Ematologia Oncologia Pediatrica) protocol
Testicular germ cell tumors (TGCT) are rare in children, and histologically and genetically similar to extragonadal tumors [1], whereas in adolescents they reveal genetic and clinical patterns similar to the disease in adults. These differences have led to TGCT being classified as type I for children with yolk sac tumor (YST) and/or teratoma (T) or type II for adolescents and young men with other, pure or mixed, sub entities [2]. In a previous Italian study [3], 36 TGCT patients ( ≤16 years old) underwent surgery, with or without radiotherapy and carboplatin-based chemotherapy (CT).
Source: Urologic Oncology: Seminars and Original Investigations - Category: Urology & Nephrology Authors: Monica Terenziani, Maria D. De Pasquale, Gianni Bisogno, Davide Biasoni, Renata Boldrini, Paola Collini, Massimo Conte, Patrizia Dall'Igna, Alessandro Inserra, Fraia Melchionda, Fortunato Siracusa, Filippo Spreafico, Francesco Barretta, Paolo D'Angelo Tags: Original article Source Type: research
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