Mild Cognitive Impairment: Associations with sleep disturbance, Apolipoprotein e4, and sleep medications

This study examined: 1) if sleep disturbance increased the hazard of MCI; 2) if APOE e4 carriers with a sleep disturbance experience an increased risk of MCI; and, 3) if prescription sleep medications provide a protective effect against MCI. We hypothesized that sleep disturbance increases the hazard of MCI, and this relationship is stronger among APOE e4 carriers reporting a sleep disturbance, and we hypothesized that sleep medications decrease the hazard of MCI.

Source: Sleep Medicine - September 20, 2018 Category: Sleep Medicine Authors: Shanna L. Burke, Tianyan Hu, Christine E. Spadola, Tan Li, Mitra Naseh, Aaron Burgess, Tamara Cadet Tags: Original Article Source Type: research