GM3 Synthase KO Mouse

Also known as:St3gal5tm1Rlp,St3gal5 KO mouseTheSt3gal5 KO mice are viable and appear grossly normal but show a heightened sensitivity to insulin. A basis for the increased insulin sensitivity in the mutant mice is enhanced insulin receptor phosphorylation in skeletal muscle. The mutant mice are protected from high-fat diet-induced insulin resistance. Learn more onPubMed.Mice can be obtained from MMRRC.
Source: NIDDK Research Resources - Category: Endocrinology Source Type: research