Therapeutic Molecules for Fumigating Inflammatory Tumor Environment

Conclusion: Although, the advanced cancer therapeutics have been established but the combination of different strategies is very important. The efficiency of the treatments depends on the stage of cancer and response of patients. Search for closely defined and selective molecular targets for a particular therapy is very complicated due to heterogenic nature of tumor environment, different therapeutic agents, incubation time, exposure doses and selectivity of therapy. The most promising photodynamic therapy (PDT) and multi- targeted therapies are being established but the question whether the cellular proteins that are most susceptible to the therapies has to be addressed. An important aspect that needs to be addressed is whether cancer is vulnerable to the particular therapy that selectively induces cell death in the cancerous tissue and inflammatory cells in tumor microenvironment that is a very challenging aspect of research in cancer treatment strategies. Hence, in this review, we focused on different therapeutic strategies for targeting multi- components of the fumigating inflammatory tumor environment.
Source: Current Signal Transduction Therapy - Category: Molecular Biology Source Type: research