Understanding age-induced cortical porosity in women: Is a negative BMU balance in quiescent osteons a major contributor?

Cortical bone is remodeled by intracortical basic multicellular units (BMUs), whose end result can be observed as quiescent osteons in histological sections. These osteons offer a unique opportunity to investigate the BMU balance between the magnitude of bone resorption and subsequent bone formation at the BMU level. Our main objective was to investigate whether the latter parameters change between defined categories of osteons and with age, and to which extend these changes contribute to age-induced cortical porosity.

Source: Bone - September 18, 2018 Category: Orthopaedics Authors: Christina M. Andreasen, Jean-Marie Delaisse, Bram C.J. van der Eerden, Johannes P.T.M. van Leeuwen, Ming Ding, Thomas Levin Andersen Tags: Full Length Article Source Type: research